University of Pavia (UNIPV)

The University of Pavia is one of the world’s oldest academic institutions: it was founded in 1361 and until the 20th century it was the only university in the Milan area and the region of Lombardy. Today 24,000 students, from both Italy and overseas, study at our University.
The University of Pavia covers all subject areas and is composed of 18 Departments offering study
programmes at all levels, from Bachelor’s degrees to Doctorate programmes. Close attention is paid to each student by our academic staff (900 professors and researchers). 87.5% of our graduates find employment within a year of graduation against a national average of 77%. Master’s degrees in the areas of science, engineering, medicine and pharmacology have a 95% post-graduation employment rate.
SilkFusion will be held at the “Laboratory of Study on Megakaryocyte Function”, directed by Prof. Alessandra Balduini, based in the “Laboratory of Biochemistry, Biotechnology and Advanced Diagnosis” of the IRCCS San Matteo Foundation of Pavia, which is part of the Unit of Clinical Biochemistry of the Department of Molecular Medicine of the University of Pavia.
The Department of Molecular Medicine was founded in 2011 with the aim to develop new interdisciplinary research programmes involving multiple Units engaged in basic laboratory research (Biochemistry, Physiology, Immunology/General Pathology) and human medical research (Genetics, Clinical Biochemistry, Pathology, Cardiology, Haematology). Nowadays, the result is a Department in which the clinical research prevails overall but that retains a strong component of basic laboratory research and aims to bridge the gap between the two halves with the aim of furthering the understanding of the molecular basis of disease and developing new diagnosis and therapies for several major diseases
Alessandra Balduini has a broad background in hematology, with specific training and expertise in research of stem cell and megakaryocyte biology, as well as in the clinical aspects of the diseases related to platelets and clotting processes. She created her research group in 2007, focusing her research on understanding how the different components of the bone marrow microenvironment regulate platelet production. This knowledge laid the groundwork for bio-engineering new 3D models made of porous silk that fully recreates the physiology of the human bone marrow niche environment. By leveraging the biocompatibility, non-thrombogenic features, programmable mechanical properties of silk, these systems allowed functional platelet production ex-vivo.
The Balduini Group includes 1 assistant professor, 4 post-doc and 1 PhD student.